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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK1
All Species:
22.12
Human Site:
S405
Identified Species:
40.56
UniProt:
Q96SB4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SB4
NP_003128.3
655
74325
S405
L
S
S
Q
N
G
D
S
S
T
S
Q
E
T
D
Chimpanzee
Pan troglodytes
XP_518428
831
92792
S581
L
S
S
Q
N
G
D
S
S
T
S
Q
E
T
D
Rhesus Macaque
Macaca mulatta
XP_001116721
831
92803
S581
L
S
S
Q
N
G
D
S
S
T
S
Q
E
T
D
Dog
Lupus familis
XP_850330
823
92006
S573
L
G
S
Q
N
G
D
S
S
T
S
Q
E
T
D
Cat
Felis silvestris
Mouse
Mus musculus
O70551
648
73070
S405
L
N
S
S
N
G
D
S
S
P
S
Q
D
T
D
Rat
Rattus norvegicus
NP_001020897
655
73837
S405
L
S
S
P
N
G
D
S
S
P
S
P
E
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516210
528
59280
Q321
E
Q
E
I
S
Q
L
Q
E
S
I
R
A
E
I
Chicken
Gallus gallus
XP_419265
754
84415
E506
S
Q
R
N
G
D
V
E
N
R
P
R
A
A
V
Frog
Xenopus laevis
NP_001085122
605
68633
M380
I
P
N
A
V
E
V
M
L
S
Q
T
S
T
V
Zebra Danio
Brachydanio rerio
NP_001074138
640
71523
T389
P
Y
P
A
C
N
G
T
E
E
T
E
P
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
I563
I
K
P
E
N
V
L
I
T
M
S
R
E
E
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
I220
F
M
H
D
L
R
M
I
H
T
D
L
K
P
E
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
N479
S
K
N
K
N
N
N
N
N
N
S
N
N
N
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
78.2
76.7
N.A.
91.4
91.4
N.A.
65.5
70.1
67.6
64.7
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
100
78.6
78.5
77.6
N.A.
94.6
94
N.A.
70.3
77.3
78.1
76.1
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
73.3
80
N.A.
0
0
6.6
0
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
80
N.A.
20
13.3
26.6
26.6
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
0
0
0
0
0
0
0
16
8
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
47
0
0
0
8
0
8
0
47
% D
% Glu:
8
0
8
8
0
8
0
8
16
8
0
8
47
16
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
47
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
16
0
0
8
0
0
0
16
0
0
8
0
0
0
16
% I
% Lys:
0
16
0
8
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
47
0
0
0
8
0
16
0
8
0
0
8
0
0
0
% L
% Met:
0
8
0
0
0
0
8
8
0
8
0
0
0
0
0
% M
% Asn:
0
8
16
8
62
16
8
8
16
8
0
8
8
8
8
% N
% Pro:
8
8
16
8
0
0
0
0
0
16
8
8
8
8
8
% P
% Gln:
0
16
0
31
0
8
0
8
0
0
8
39
0
0
0
% Q
% Arg:
0
0
8
0
0
8
0
0
0
8
0
24
0
0
0
% R
% Ser:
16
31
47
8
8
0
0
47
47
16
62
0
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
8
8
39
8
8
0
54
0
% T
% Val:
0
0
0
0
8
8
16
0
0
0
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _